DOMEK is a multi-step pipeline which leverages mRNA display-derived next-generation sequencing data to derive kinetic information about substrates of post-translational modification enzymes.

Abstract: Reliable methods for the neurodevelopmental assessment of infants are essential for early detection of problems that may need prompt interventions. Spontaneous motor activity, or ‘kinetics’, ...

This valuable study presents the development of a single turnover stopped-flow fluorescence experiment to study the kinetics of substrate unfolding and translocation by the bacterial ClpB disaggregase ...

Biocatalysis is becoming a data science. High-throughput experimentation generates a rapidly increasing stream of biocatalytic data, which is the raw material for mechanistic and novel data-driven ...

This study presents an assessment of the effect of lactate dehydrogenase (LDH) inhibition on the activity of glycolysis and tricarboxylic acid cycle. The data were collected and analyzed using solid ...

Sign up for CNN’s Eat, But Better: Mediterranean Style. Our eight-part guide shows you a delicious expert-backed eating lifestyle that will boost your health for ...

Enzyme kinetics is a crucial topic in the field of biochemistry, and Lineweaver-Burk plots provide valuable insights into the behavior of enzymes. Understanding how to interpret these plots is ...

Understanding enzyme kinetics is crucial in various scientific fields, such as biochemistry, pharmacology, and biotechnology. One of the essential components in enzyme kinetics is the maximum velocity ...

The enzyme-catalyzed reaction rate is an essential parameter in molecular biology, biochemistry, and biotechnology. One of the main parameters used to describe enzyme efficiency is kcat, also known as ...