The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

Mutations in DNA during its replication — copying errors — drive evolution. But, in simple organisms such as bacteria, the genetic code may also evolve through the transfer of genetic material from ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the DNA ...

Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

Six feet of DNA crammed into a cell nucleus narrower than a human hair: ...