The versatile nucleotide excision repair (NER) pathway removes helix-distorting DNA damage in a multistep 'cut and patch'-type reaction. Two damage detection subpathways exist: global genomic NER ...

Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents.

Nucleotide excision repair is a process that repairs damage to one strand of the DNA, particularly from UV irradiation, which distorts the DNA helix. The DNA flanking the damage site is cleaved to ...

DNA repair can be divided into a set of mechanisms that identify and correct damage in DNA molecules. There are two general classes of DNA repair; the direct reversal of the chemical process ...

Hailin Wang, Meiling Lu, Moon-Shong Tang, Bennett van Houten, J. B. Alexander Ross, Michael Weinfeld, X. Chris Le, Philip C. Hanawalt Proceedings of the National ...

This is a preview. Log in through your library . Abstract We have adapted the eXcision Repair-sequencing (XR-seq) method to generate single-nucleotide resolution dynamic repair maps of UV-induced ...

Damage to your DNA is unavoidable. Every day our cells are bombarded by gene-splitting UV radiation or chemical carcinogens. Regular water inside our bodies can cause DNA damage. DNA damage is as ...