To make the technique work in cultured mammalian cells, researchers must deliver small interfering RNAs (siRNAs), which are dsRNAs of 21-25 nucleotides, to the cell. They can use a wide range of ...

Single-Source Systems, Sample Prep, RNA Amplification, and RNAi Seen as Key Trends Good-quality RNA impacts downstream analysis and results, explains Lucy Sha, marketing director for gene and protein ...

Researchers at Duke University (NC, USA) have developed CellREADR, a new piece of RNA-based editing technology that operates by targeting cells instead of genes. CellREADR is a string of RNA comprised ...

Ever since the discovery of DNA’s double-helix structure, life scientists have been interested in somehow introducing foreign nucleic acid molecules into a host cell and expressing the genes encoded ...

Transfection alters the genetic makeup of eukaryotic cells by introducing foreign nucleic acids, including DNA, RNA, and small noncoding RNAs such as siRNA, shRNA, and miRNA. Scientists use ...