Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

Researchers at the University of Toronto's Temerty Faculty of Medicine have found widespread genetic and protein changes in the brain cells of people with amyotrophic lateral sclerosis (ALS), which ...

BIRMINGHAM, Ala. – RNA transcription is the genomic process in which a cell produces a duplicate of a gene’s DNA sequence. Present in both DNA and RNA sequences, a G-quadruplex (GQ) is a structure of ...

Researchers have identified a stress-activated control mechanism that helps breast cancer cells reshape gene activity to ...

New modelling and single-cell analyses reveal how bacterial RNA repair shapes variable responses to ribosome-targeting ...

From enzymes and lipid nanoparticles to large-scale process design, four global innovators redefine RNA-based medicine development and delivery.

As animals and people age, there are changes in the genome. Telomeres, the protective ends of chromosomes, get shorter as cells continue to divide; some cells will pick up mutations in their genomes ...